Although the body is protected by the immune system, only a small proportion of people do not experience inflammatory problems in their lives. For girls, preventive Babeş–Pap smear tests are necessary, and vaccination against oncogenic HPV strains must be considered. The treatment of symptoms and effects of these ailments without removing their causes make them sometimes change into diseases of disastrous consequences leading to a tragedy of many women and their families. It is therefore important to prevent diseases by prophylactic checkups and treatment of diagnosed pathological conditions. The most certain methods enabling sexually transmitted diseases to be avoided are refraining from sexual activity (vaginal, anal or oral) or remaining in a long-term monogamous relationship with an uninfected partner. Prior to the initiation of sexual activity, it is recommended to perform tests for sexually transmitted diseases, including HIV infection. According to numerous reports, about one million people a day are infected with a sexually transmitted disease. The WHO (World Health Organization) reports that recent changes and new trends in the epidemiology are as follows: 340 million new cases each year (an increase by 50% since 1990), including more than 50% of patients at the age <25. According to the WHO, 41% of patients <25 years old have unprotected sex. The estimated number of new cases of sexually transmitted infections in the US is 9.1 million infections per year among persons <25 years old; 88% of them being HPV (human papillomavirus), NG (Neisseria gonorrhoeae), TV (Trichomonas vaginalis) or CT (Chlamydia trachomatis) infection. In Eastern Europe a 37-fold increase in syphilis has been noted in the past 10 years. Demographic and educational changes as well as behavioral factors are important and affect the incidence of sexually transmitted diseases.