Analysis of selected clinical and histological factors predisposing to tumor recurrence after primary treatment of planoepithelial vulvar cancer
Affiliation and adress for correspondence

1 I Katedra i I Klinika Położnictwa i Ginekologii WUM, pl. Starynkiewicza 1/3, Warszawa
2 Klinika Nowotworów Narządów Płciowych Kobiecych, Centrum Onkologii – Instytut im. Marii Skłodowskiej-Curie w Warszawie.
Kierownik Kliniki: prof. dr hab. n. med. Mariusz Bidziński
Correspondence to: Prof. dr hab. n. med. Mariusz Bidziński, Klinika Nowotworów Narządów Płciowych Kobiecych, Centrum Onkologii
– Instytut im. Marii Skłodowskiej-Curie, ul. Roentgena 5, 02-781 Warszawa, tel.: 022 546 22 95, e-mail: mbidzinski@coi.waw.pl
Source of financing: Department own sources

CURR. GYNECOL. ONCOL. 2009, 7 (3), p. 161-168
ABSTRACT

Aim of paper: Analysis of selected clinical and histological factors predisposing to local or regional-nodal recurrence in patients after primary treatment of planoepithelial vulvar cancer. Material and methods: Study population consisted of 34 women aged 37-93 years, operated on for planoepithelial vulvar cancer. Most patients underwent radical vulvectomy with bilateral inguinal lymphadenectomy. An indication for adjuvant radiotherapy was non-radical tumor excision or presence of metastases in inguinal lymph nodes. Results: Seven patients were excluded from study population. Recurrence occurred in 9 out of 27 patients (33.3%) aged 59-93 years . In 3 cases, recurrence developed at the place of inguinal lymph nodes, while in 6 – at the place of excised vulva. Out of 10 women (37%) with inguinal lymph node metastases, 5 patients (50%) developed a recurrence. Conclusions: Metastases to inguinal lymph nodes developed significantly more often in primary tumors exceeding 5 cm in diameter. Recurrence of vulvar cancer developed significantly more often in patients with late-stage disease process. Local recurrence of vulvar cancer developed significantly more often in patients with non-radical margin of excision, which in turn was more frequently seen in patients with tumors exceeding 3 cm in diameter.

Keywords: planoepithelial vulvar cancer, treatment, recurrence, clinical factor, histological factor